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diagnosis differential management neurology autoimmune complications cord disorders erythematosus lupus musculoskeletal myelitis rheumatology sams signs spinal spinalcord statin systemic toxicity
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
- Myositis ... femoral heads • Myopathy ... #MSK #Musculoskeletal ... Complications #pathophysiology ... #signs #symptoms
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Necrotizing myopathy ... associated with higher CK ... greater level of muscle ... less systemic symptoms ... Can also see mechanics
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... • Myalgia • Myositis ... erythematosus (SLE ... inclusion body myositis ... Diagnosis: • CK
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
findings: • Symptoms ... - Transverse myelitis ... - Radiation myelopathy ... Behcet disease - SLE ... differential #algorithm
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... the spinal cord (Myelopathy ... Bilateral signs and/or symptoms ... Evaluate for NMO, SLE ... Disorders: - SLE
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