25 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
- Myositis ... Weakness, Incr CK ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... associated with higher CK ... greater level of muscle ... less systemic symptoms ... triad of ILD, myositis
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... • Myalgia • Myositis ... inclusion body myositis ... Diagnosis: • CK ... myopathy #diagnosis #management
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... which impairs musde ... Asymptomatic CK ... Hypothyroid #Myopathy #pathophysiology ... #signs #symptoms
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs and Symptoms ... can happen) • Muscle ... reflexes (at those muscles ... Radiculopathy #MSK ... #pathophysiology
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
tensile strength of muscle ... damage to nerves, muscles ... Diagnosis #signs #symptoms ... #msk #orthopedics ... #pathophysiology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
- Elevation of muscle ... Creatinine kinase (CK ... - Bilateral Muscle ... PM #Diagnosis #Pathophysiology ... #Signs #Symptoms
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
• Hypothenar muscle ... Syndrome #Diagnosis #pathophysiology ... #signs #symptoms ... #msk
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Tests: • Measure CK ... (symmetric) • CK ... weakness • CK ... Very high serum CK
Myositis on POCUS
Which of the following is the best choice for management for this patient?
Resolution: steroids
Myositis on POCUS ... best choice for management ... this patient with myositis ... clinical #ultrasound #MSK ... #Muscle
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