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differential rheumatology signs erythematosus lupus management systemic temporal arthropathies arthropathy ascorbicacid autoimmune classification complications cranialarteritis dermatomyositis disorders dm giantcell giantcellarteritis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
- Arthralgia, Arthritis ... #MSK #Musculoskeletal ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... skin lesions - Muscle-soreness ... #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... Algorithm Monoarthritis ... Erythematosus (SLE ... should have other symptoms ... Joint #Disorders #msk
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
associated with higher CK ... greater level of muscle ... less systemic symptoms ... myositis, and arthritis ... Can also see mechanics
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Joints: myalgia and muscle ... Differential Diagnosis ... Presentation - Systemic Symptoms ... , and SLE) • Urinalysis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Creatinine kinase (CK ... Polymyositis #PM #Diagnosis ... #Pathophysiology ... #Signs #Symptoms ... #Vasculitis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... diseases, such as SLE ... Presentation: Systemic Symptoms ... • Progressive symptoms
Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings - Morning Stiffness (>1
Giant Cell Arteritis ... Stiffness (>1 hr) - Muscle ... CranialArteritis #Pathophysiology ... #Signs #Symptoms ... #Diagnosis #Vasculitis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (SCLE ... Differential Diagnosis ... ANCA-associated vasculitis ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... musculoskeletal symptoms ... Psychiatric symptoms ... nonimmune hemolysis MSK ... • Weakness • Muscle
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