7 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... 80%) - Proximal Weakness ... femoral heads • Myopathy ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... weakness • Soreness ... syndrome (GBS), systemic ... syndrome (LEMS), systemic ... Diagnosis: • CK
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... associated with higher CK ... greater level of muscle ... weakness, less ... systemic symptoms
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
entire spinal cord ... - Signs and Symptoms ... Hypertonicity (muscles ... • Gross motor weakness ... #msk
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
findings: • Symptoms ... /paralysis - Weakness ... - Radiation myelopathy ... , Scleroderma, Systemic ... differential #algorithm
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tests: • Measure CK ... (symmetric) • CK ... weakness • CK ... weakness PE: Muscle ... • Conduction system
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
Evaluation of Recurrent ... Falls Core Concept ... presyncope, exertional symptoms ... • Clues: Focal weakness ... , muscle wasting