49 results
diagnosis management signs differential neurology pathophysiology rheumatology treatment syndrome lupus myopathy radiology rhabdomyolysis sle algorithm anterior comparison cord disorders erythematosus
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Weakness, Incr CK ... Osteoporosis #Systemic ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... associated with higher CK ... greater level of muscle ... weakness, less systemic ... symptoms, and less
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Causes of Elevated CK ... Levels Acute CK ... immobility • Critical ... ): • PROXIMAL MUSCLE ... myopathy - Autoimmune
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... syndrome (GBS), systemic ... syndrome (LEMS), systemic ... Diagnosis: • CK ... IU/I • SAMS clinical
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
autoimmune disease ... Lupus - with Systemic ... should have other symptoms ... Amy Chung, MD, MSc ... Joint #Disorders #msk
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
which impairs musde ... fibers Spectrum of Clinical ... Asymptomatic CK ... proximal myopathy → Muscle ... pathophysiology #signs #symptoms
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Pathogenesis and clinical ... - Elevation of muscle ... Creatinine kinase (CK ... - Bilateral Muscle ... Pathophysiology #Signs #Symptoms
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Pathogenesis, clinical ... tensile strength of muscle ... damage to nerves, muscles ... Diagnosis #signs #symptoms ... #msk #orthopedics
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... likely it will be clinically ... Disorders, Infection, Autoimmune ... Thyroid, Autoimmune
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Tests: • Measure CK ... (symmetric) • CK ... weakness • CK ... • Conduction system
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