105 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Weakness, Incr CK ... Osteoporosis #Systemic ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... symptoms: weeks ... syndrome (GBS), systemic ... syndrome (LEMS), systemic ... Diagnosis: • CK
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
associated with higher CK ... greater level of muscle ... weakness, less systemic ... symptoms, and less
SNOOP mnemonic may catch potentially life-threatening headaches
Systemic signs and disorders
Neurologic symptoms
Onset new or changed & patient
life-threatening headaches Systemic ... and disorders Neurologic ... symptoms Onset ... redflag #dangerous #neurology
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Myopathy - Proximal muscle ... involvement, elevated CK ... Weakness #Sensory #Neurology
Approach to Headache - Differential Diagnosis Framework
Red Flags (SNOOPY)
S: Systemic Symptoms
N: Neuro Symptoms
O: Onset - Sudden
O:
Flags (SNOOPY) S: Systemic ... Symptoms N: Neuro ... Symptoms O: Onset ... Diagnosis #algorithm #neurology
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs and Symptoms ... can happen) • Muscle ... reflexes (at those muscles ... Radiculopathy #MSK ... diagnosis #signs #symptoms
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
pannus formation, systemic ... Lupus - with Systemic ... should have other symptoms ... Amy Chung, MD, MSc ... Joint #Disorders #msk
Peripheral Nervous System Disorders

1 Anterior Horn Cell
2 Spinal Roots and Nerves 
3 Peripheral Nerve—Mono-neuropathy  
4
Peripheral Nervous System ... Neuromuscular Junction 6 Muscle ... Nerve #Neuropathy #Neurology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Myopathy - Proximal muscle ... involvement, elevated CK ... Peripheral #Weakness #Neurology