6 results
diagnosis oncology algorithm chronic cll differentiation emergencies hemeonc hypercoagulable lymphocytic mds myelodysplasia myelodysplastic oncologic syndrome syndromes thromboembolism
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
- No other workup ... cancer screening, CBC ... , aPTT, +/- CXR ... #hematology #diagnosis ... #algorithm #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... APML, CLL Acute ... manifestations, hypoxia, CXR ... smear: Blasts APML ... #Hematology #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
common • Imaging: CXR ... - pulmonary opacities ... Differentiation #Syndrome #APML ... #diagnosis #management ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Lymphocytosis on CBC ... Transform to DLBCL, PML ... #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... (CML) • Felty ... • Hairy Cell Leukemia ... Workup: • Complete ... Syndromes #diagnosis #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... Usually myeloid leukemias ... renal failure, pulmonary
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