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diagnosis oncology algorithm chronic hemeonc lymphocytic aecopd apml classification copd differentiation emergencies exacerbation hodgkins hypercoagulable lymphoma mds myelodysplasia myelodysplastic oncologic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... involvement CML ... ↓ LAP Score • CML ... manifestations, hypoxia, CXR ... #Hematology #Oncology
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
- No other workup ... cancer screening, CBC ... , aPTT, +/- CXR ... #hematology #diagnosis ... #algorithm #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL ... Lymphocytosis on CBC ... leukemia #CLL ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... • Most common leukemia ... Vmphocytosis on routine CBC ... #oncology #hematology ... hemeonc #diagnosis #management
Algorithm for Management of Acute Exacerbation of COPD (AECOPD) Obtain workup for alternate diagnoses and relevant comorbidities:
AECOPD) Obtain workup ... comorbidities: • CBC ... limitation (GOLD Ill ... ventilated • CXR ... Exacerbation #treatment #pulmonary
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Induce blast cell ... common • Imaging: CXR ... - pulmonary opacities ... APML #diagnosis #management ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... (CML) • Felty ... Leukemia • Idiopathic ... Workup: • Complete ... Syndromes #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Hodgkin Lymphoma Workup ... cycles without XR ... classification #hematology ... #oncology #management
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... Usually myeloid leukemias ... renal failure, pulmonary
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