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diagnosis algorithm chronic cll hemeonc lymphocytic anemia anticoagulation aplastic apml cancer classification differentiation doac emergencies hodgkins hypercoagulable lymphoma malignancy mds
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
- No other workup ... cancer screening, CBC ... , aPTT, +/- CXR ... #hematology #diagnosis ... #algorithm #hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
thrombosis; PE = pulmonary ... body mass index; VTE ... #DOAC #VTE #Malignancy ... Anticoagulation #Management ... #Hematology #Oncology
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 Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... involvement CML ... ↓ LAP Score • CML ... manifestations, hypoxia, CXR ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... • Most common leukemia ... Lymphocytosis on CBC ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... Vmphocytosis on routine CBC ... #oncology #hematology ... hemeonc #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
5 or elevated Cr ... common • Imaging: CXR ... - pulmonary opacities ... APML #diagnosis #management ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- EBV - CMV ... virus (EBV) • Leukemia ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... Usually myeloid leukemias ... renal failure, pulmonary
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... cycles without XR ... ABVD x 2 cycles + XR ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... (CML) • Felty ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
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