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differential hematology monoclonal syndrome gammopathy management significance aids associated barre behcet cauda caudaequina causes clinical dementia disease disorder equina gammopathies
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... - Differential Diagnosis ... Neurologic-Centered ... #Differential #Diagnosis ... #hematology #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... et diutinum Neurologic ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Significance (MGUS ... IgM MGUS: • Serum ... constitutional symptoms ... #Significance #hematology ... #diagnosis #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
focal lesions on MRI ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... thrombosis, VTE) • Cardiac ... management #signs #symptoms ... #rheumatology #
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... Differential Diagnosis ... perineum, and posterior ... #causes #neurology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
• Depressive symptoms ... similar to PML, but MRI ... Diagnosis: MRI ... white matter and posterior ... dementia #AIDS #Neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
MANIFESTATIONS: • The cardinal ... bulbar muscles DIAGNOSIS ... than one after symptom ... Barre #Syndrome #diagnosis ... #management #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Presentation: Systemic Symptoms ... affects the skin, neurologic ... • Progressive symptoms ... #Rheumatology
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