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diagnosis treatment differential fungal hematology infectiousdiseases neurology aspergillus autoimmune bee cerebritis coagulation dic emergencies erythematosus hemeonc ia infections inflammatory intravascular
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
nervous system (CNS ... and less common diseases ... Inflammatory causes ... • Acute disseminated ... polychondritis • Behcet disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Cerebrovascular Disease ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... first) DIC (disseminated ... Treat underlying cause ... ) - Symptoms: CNS ... ) - Symptoms: CNS
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... malignancy (Especially acute ... Thromboembolism (7%) • CNS ... • Severe Liver Disease ... #treatment #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... #Rheumatology # ... Diagnosis #Management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... involvement • 30%: CNS ... : CNS manifestations ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Diagnosis and Management ... Rhinosinusitis, CNS ... Gastrointestinal, Disseminated ... septated hyphae, acute ... vori Infectious Diseases
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
presents with acute ... pulmonary symptoms • Rheumatologic ... especially the CNS ... MC: CNS CSF: • ... Fungal #Diagnosis #Management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... Polymyositis or ALS ... nucleotidase 1A (Anti cN ... statins - probably caused ... Myositis #Myopathy #rheumatology
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