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diagnosis hematology treatment acute all behcet causes coagulation disease disseminated emergencies hemeonc intravascular lymphoblastic oncologic peds signs sjogrens symptoms timeline
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia Induction: • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate Consolidation
Lymphoblastic Leukemia ... Consolidation & CNS ... Treatment #timeline #oncology ... #pediatrics #peds ... #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... : CNS manifestations ... Fibrinolysis & DIC ... • Tumor lysis syndrome ... #Hematology #Oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... G6PD first) DIC ... Usually myeloid leukemias ... ) - Symptoms: CNS ... ) - Symptoms: CNS
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation (DIC ... promyelocytic leukemia ... Thromboembolism (7%) • CNS ... causes #treatment #management ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... tears, Ischemia, Leukemia ... collaboration • CNS ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... #Rheumatology # ... Diagnosis #Management
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