19 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Puncture, EEG Treatment ... Systemic #Lupus #Erythematosus ... #rheumatology # ... diagnosis #management #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... involve PNS and CNS ... extremities Drug ... • Antihistone: Drug ... #Diagnosis #Rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Systemic lupus erythematosus ... disease (MCTD), Drug-induced ... Systemic lupus erythematosus ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
the lung) - CNS ... hemorrhage) - Pulmonary ... exacerbation) - Drugs ... Differential #Diagnosis #Table
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Systemic Lupus Erythematosus ... life-threatening • Treatment ... sle #comparison #table ... #rheumatology #
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
, wt loss; CV, CNS ... Fever, wheezing • Drug ... antibiotics, illicit drugs ... Lung #Diseases #pulmonary ... diagnosis #comparison #table
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus erythematosus ... nervous system (CNS ... ) • Sepsis • Drug-induced ... Treatment: • Corticosteroids ... #Rheumatology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
Infarction and Pulmonary ... associated with rheumatologic ... systemic lupus erythematosus ... Presentation #comparison #Table
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Drug Induced Systemic ... Lupus Erythematosus ... for 1 year of treatment ... Systemic #Lupus #Erythematosus ... differential #diagnosis #rheumatology