21 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS ... #neurology #rheumatology ... diagnosis #management #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... constitutional symptoms • Treatment ... life-threatening • Treatment ... sle #comparison #table ... #rheumatology #
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SLE : systemic lupus ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
disease (MCTD), Drug-induced ... Idiopathic Arthritis, Drug-Induced ... Biliary Cirrhosis, Drug-Induced ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic lupus ... Farr assay) and lupus ... SLE (60-70%) & drug-induced ... erythematosus #diagnosis #rheumatology ... #table #ANA
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
the lung) - CNS ... hemorrhage) - Pulmonary ... exacerbation) - Drugs ... Differential #Diagnosis #Table
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
, wt loss; CV, CNS ... Fever, wheezing • Drug ... antibiotics, illicit drugs ... Lung #Diseases #pulmonary ... diagnosis #comparison #table
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... SJIA], systemic lupus ... ) • Sepsis • Drug-induced ... Treatment: • Corticosteroids ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... involve PNS and CNS ... extremities Drug ... • Antihistone: Drug ... Erythematosus #Diagnosis #Rheumatology