15 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... /systemic sclerosis ... Hydroxychloroquine *Short ... #Summary #diagnosis ... #rheumatology #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Erythematosus (SLE ... Cerebrovascular Disease ... #management #treatment
Cardiomyopathies 

Manifestations of cardiomyopathy (CM) range from microscopic alterations in cardiac myocytes to fulminant Heart Failure
Tachycardia (CPVT) • Short ... of generalized systemic ... Hemochromatosis, Fabry's disease ... Autoimmune/collagen (SLE ... Cardiomyopathies #cardiology #diagnosis
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
• Autoimmune (SLE ... Vascular: • Systemic ... nodes • Roth’s spots ... underlying cause + Systemic ... #diagnosis #management
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
conditions: Autoimmune (SLE ... features: Fever -, Systemic ... features: Fever +, Systemic ... - Infectious Diseases ... #table
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... and CNS • Headache ... • Libman-Sacks endocarditis ... Erythematosus #Diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... basal ganglia, CNS ... Oral aphthae : SLE ... • Arthritis: SLE ... #management #signs
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... (CNS) dysfunction ... erythematosus [SLE ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
months to years) Systemic ... : Chronic disease ... #comparison #table ... #rheumatology #diagnosis ... #management
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... LV thrombus, RV systolic ... orthopnea, PND, LE ... Delivery • Stable ... #diagnosis #management