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ana antibodies causes disease erythematosus management myopathy myositis patterns signs sle symptoms syndrome systemic adies algorithm arthritis autoantibodies autoimmune behcet
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Homogeneous: Systemic lupus ... , Drug-induced Lupus ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Sjögren Syndrome, Myositis ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology ... #diagnosis #differential
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
anemia 4% - Myositis ... (aPL) 30-45% Differential ... Diagnosis and Lupus ... symptoms #mimickers #differential ... #rheumatology
Differential diagnoses for the neuro-ophthalmologic finding of diplopia. Neoplastic: • Intraorbital meningioma • Pituitary adenoma
Differential diagnoses ... for the neuro-ophthalmologic ... #Diplopia #Differential ... #Diagnosis #Causes ... #Ophthalmology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... and CNS • Headache ... • Transverse Myelitis ... #Rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Diagnosis Algorithm ... Autoimmune Vasculitis (lupus ... Measurement of antinuclear ... #dermatology #physicalexam
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Scleromyxedema (CNS ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Adie's Pupil What? Unknown nature & benign • Regular and mildly dilated pupil (4-6mm); • Light-near dissociaton;
Young females Differential ... Diagnosis: • CN ... #Adies #Pupil #PhysicalExam ... #neurology #ophthalmology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... Behcet disease) Differential ... inhibitors • Uveitis- Ophthalmology ... signs #symptoms #rheumatology
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