10 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE ... the formation of autoantibodies ... #rheumatology # ... #management #treatment
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Rheumatology • ... Lupus (SLE): ANA ... Peptide (CCP) • Myositis ... diagnosis #associations
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
anemia 4% - Myositis ... involvement 3% SLE-Related ... Lupusreference #SLE ... #autoantibodies ... #differential #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
months) and of autoantibodies ... Usual therapeutic management ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Anti-Ro/SSA autoantibodies ... and CNS • Headache ... • Transverse Myelitis ... #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Oral aphthae : SLE ... • Arthritis: SLE ... inhibitors • Uveitis- Ophthalmology ... #management #signs ... #symptoms #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... erythematosus [SLE ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... neuropathy, transverse myelitis ... • 8%-27% for CNS ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... months) and of autoantibodies ... #DIL #rheumatology ... #diagnosis #treatment ... #management
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
including systemic lupus ... erythematosus (SLE ... Histopathological Diagnoses ... agonists #TAFRO #diagnosis ... #management #rheumatology