10 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Necrotizing myopathy ... less systemic symptoms ... and anti-HMGCR myopathy ... after 2 years of treatment ... #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Aseptic Meningitis, Myelopathy ... permeability Diagnosis ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... GBS), systemic lupus ... Atorvastatin Diagnosis ... #diagnosis #management ... #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... and CNS • Headache ... • Transverse Myelitis ... : • Symptoms limited ... #Rheumatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... the spinal cord (Myelopathy ... Bilateral signs and/or symptoms ... Diagnosis: • ... Treatment: •
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
symptoms (headache ... Arthritis, AS Treatment ... inhibitors • Uveitis- Ophthalmology ... management #signs #symptoms ... #rheumatology #
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... equina syndrome (CES ... Differential Diagnosis ... • Transverse myelitis ... axial T1 and T2 Treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
demyelinating disease, myelopathy ... neuropathy, transverse myelitis ... • 8%-27% for CNS ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... myopathies Diagnostic ... RP-ILD), dermato-rheumatologic ... nucleotidase 1A (Anti cN ... #Myopathy #rheumatology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
including systemic lupus ... and the systemic symptoms ... Histopathological Diagnoses ... Hypoalbuminemia Treatment ... #management #rheumatology