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differential neurology management rheumatology video signs symptoms causes treatment ophthalmology syndromes msk nephrology pathophysiology algorithm endocrinology erythematosus lupus orthopedics pulmonary
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Diagnosis Framework ... pulmonary etc) • CNS ... • Acute stroke syndromes ... Paraneoplastic syndrome ... #Differential #Diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... Other brainstem syndromes ... • Transverse myelitis ... pain • Extra-CNS ... Manifestations #diagnosis
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Tetanus, Transverse Myelitis ... Guillain-Barre syndrome ... heavy metals), Critical ... #differential #diagnosis
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
level of muscle weakness ... anti-synthetase syndrome ... /full triad at diagnosis ... have significant weakness ... #diagnosis #rheumatology
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... Anti-Synthetase Syndrome ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... - Clinical Presentation ... Weakness: - Weakness ... bouts of HTN Diagnostic ... Diagnosis: •
CN III Palsy - Oculomotor Nerve • Ptosis: Loss of innervation of the levator palpebrae superior.
CN III Palsy - Oculomotor ... comparison to Horner's syndrome ... Extraocular Muscle Weakness ... neudrawlogy #CNIII #CN3 ... Cranial #neurology #diagnosis
Hypothyroidism – symptoms and signs. Symptoms: Tiredness/malaise, Weight gain, Anorexia, Cold intolerance, Poor memory, Change in appearance, Depression, Poor libido,
Myalgia, Muscle weakness ... of movement, Deafness ... Carpal timel syndrome ... Signs #Symptoms #Diagnosis ... #PhysicalExam #
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Associated Features: Diagnosis ... Associated Features: Weakness ... over years, often diagnosed ... #differential #diagnosis ... #rheumatology #table
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Generalized Weakness ... - Differential Diagnosis ... Rhabdomyolysis, Critical ... Inflammatory/Rheum: Myositis ... #Generalized #Weakness
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