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differential erythematosus sle systemic algorithm ana antinuclear arthritis associations autoantibodies causes classification criteria dermatology disease eularacr laboratory management manifestations myopathy
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... others (RNP, aPL antibodies ... #diagnosis #associations ... #table
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... Sjögren Syndrome, Myositis ... ANA #patterns #rheumatology ... #diagnosis #differential
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
• Transverse myelitis ... pain • Extra-CNS ... , Comorbid autoimmune ... disorders (Systemic lupus ... #neurology #symptoms
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
least 2 joints • Neurologic ... Thrombocytopenia, Autoimmune ... Highly specific antibodies ... Erythematosus #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... rheumatologic diseases ... and CNS • Headache ... • Transverse Myelitis ... #Rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Palpable Rash: - Autoimmune ... Vasculitis (lupus ... blood test • Serology ... #dermatology #physicalexam
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... nervous system (CNS ... neuropathy, transverse myelitis ... • 8%-27% for CNS ... Sjogrens #Syndrome #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... - Differential Diagnosis ... RP-ILD), dermato-rheumatologic ... nucleotidase 1A (Anti cN ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... double-stranded DNA antibodies ... (to support a diagnosis ... #testing #Rheumatology
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