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differential autoantibodies erythematosus sle symptoms systemic arthritis associations autoimmune disease laboratory management manifestations mimickers myopathy myositis neuromyelitis nmo optica rheumatic
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... others (RNP, aPL antibodies ... #diagnosis #associations ... #table
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Diagnosis Manifestations ... anemia 4% - Myositis ... SLE-Related Auto-Antibodies ... autoantibodies #signs ... #differential #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
• Transverse myelitis ... pain • Extra-CNS ... disorders (Systemic lupus ... #neurology #symptoms ... #signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... and CNS • Headache ... • Transverse Myelitis ... #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... • Bilateral signs ... Diagnosis: • ... Antiamphiphysin antibodies ... #neurology #differential
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... double-stranded DNA antibodies ... (to support a diagnosis ... #testing #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... nucleotidase 1A (Anti cN ... #Myopathy #rheumatology
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