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management lupus differential erythematosus neurology signs sle symptoms syndrome antinuclear autoantibodies disease hematology treatment activation antibodies arthritis associations autoimmune behcet
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Peptide (CCP) • Myositis ... • Scleroderma (Systemic ... #diagnosis #associations ... #table
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... • Transverse myelitis ... pain • Extra-CNS ... autoimmune disorders (Systemic ... Manifestations #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Erythematosus (SLE) Clinical ... permeability Diagnosis ... #neurology #rheumatology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Associated Features: Diagnosis ... Pattern: Proximal and ... #differential #diagnosis ... #comparison #rheumatology ... #table
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... • Homogeneous: Systemic ... Sjögren Syndrome, Myositis ... #patterns #rheumatology ... #diagnosis #differential
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
fever syndromes Clinical ... Fever is the main clinical ... (CNS) dysfunction ... Activation #Syndrome #Diagnosis ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... and CNS • Headache ... • Transverse Myelitis ... #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... association • M > F Clinical ... basal ganglia, CNS ... Behcet syndrome (Clinical ... signs #symptoms #rheumatology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
or Infarction and ... associated with rheumatologic ... presentation of systemic ... #Presentation #comparison ... #Table #Diagnosis
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 Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... Parotid swelling CNS ... neuropathy, transverse myelitis ... • 8%-27% for CNS ... Sjogrens #Syndrome #Rheumatology
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