105 results
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... Inclusion Body Myositis ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Anemia (AIHA) - Differential ... Diagnosis Table ... #Anemia #AIHA #Differential ... #Diagnosis #Table ... #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Lymphadenopathy, CNS ... Blood #Disorders #hematology ... #Diagnosis #Algorithm
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Associated Features: Diagnosis ... Inflammatory #Myopathies #differential ... #diagnosis #comparison ... #rheumatology # ... table
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Dyspnea - Differential ... Diagnosis Framework ... - Transverse myelitis ... • Hematology: ... #diagnosis #causes
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Diagnosis Framework ... pulmonary etc) • CNS ... #Weakness #Differential ... #Diagnosis #neurology
Diagnosis and management of Polyarteritis Nodosa (PAN)

Chapel Hill 2012 definition: 
Necrotizing vasculitis ofmedium or small arteries
Diagnosis and management ... Cardiomyopathy - CNS ... PolyarteritisNodosa #Rheumatology ... #Diagnosis #Management ... #Vasculitis #Differential
Nail diseases and disorders.
 - Spoon Nails (Koilonychia)
 - Pitting of Nails
 - Beau's Lines
 -
white spots) #Diagnosis ... Fingernail #Disorders #Differential ... #Leukonychia #Table ... #Clinical #PhysicalExam
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Myositis and Myopathies ... Inclusion Body Myositis ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... • Transverse myelitis ... pain • Extra-CNS ... positive NMO only): Myositis ... Manifestations #diagnosis