25 results
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... Inclusion Body Myositis ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Lymphadenopathy, CNS ... Blood #Disorders #hematology ... #Diagnosis #Algorithm
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Associated Features: Diagnosis ... Inflammatory #Myopathies #differential ... #diagnosis #comparison ... #rheumatology # ... table
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... - Clinical Presentation ... bouts of HTN Diagnostic ... Diagnosis: • ... #neurology #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
anemia 4% - Myositis ... (aPL) 30-45% Differential ... Other auto-immune, Infectious ... symptoms #mimickers #differential ... #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Syndrome (CAS ... Clinical Presentation ... younger pts) Differential ... hemolytic #anemia #hematology ... #diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
e.g., HIV), EBV infection ... Etiology: - Infections ... Diagnosis of B-Symptoms ... #differential # ... hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... Diaqnoses: • ... Infectious: Mycoplasma ... management #treatment #rheumatology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Immunocompromised Host - Differential ... Diagnosis Algorithm ... jirovecii • CNS ... #Diagnosis #Algorithm ... #Causes #Hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... Neutrophil (Normal) Differential ... likelihood of negative clinical ... #Bandemia #differential ... #WBC #CBC #hematology