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differential management erythematosus lupus systemic algorithm autoantibodies autoimmune behcet cmv comparison cord cytomegalovirus disease disorders endocarditis fungal hiv infectiousdiseases infective
Cytomegalovirus (CMV) in HIV-AIDS Patients Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family. CMV infection: virus isolation or detection
CMV infection: virus ... or signs. ... 50 or less: • Neurologic ... Encephalitis, Myelitis ... #signs #symptoms
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... • Bilateral signs ... and/or symptoms ... Disorders: - SLE ... #neurology #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
anemia 4% - Myositis ... Other auto-immune, Infectious ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... symptoms (headache ... Oral aphthae : SLE ... #management #signs ... #symptoms #rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... yeast • At risk: AIDS ... especially the CNS ... MC: CNS CSF: • ... : • Serology for
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... - Transverse myelitis ... Infections: - ... Behcet disease - SLE ... #neurology #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... fibromyalgia) • Infections ... • Transverse Myelitis ... Induced Lupus: • Symptoms ... #Rheumatology
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... /symptoms or echo ... conditions: Autoimmune (SLE ... large infarct - Infectious ... #table
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... purpura: Strong sign ... • Progressive symptoms ... chorioretinitis, CNS ... #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tenderness → Consider infectious ... RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... #Myopathy #rheumatology
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