13 results
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... Many others • Transverse ... pain • Extra-CNS ... diagnosis #neurology #symptoms ... #signs
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... symptoms (headache ... Behcet disease) Differential ... diagnosis #management #signs ... #symptoms #rheumatology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... (CES) is usually ... - Emergency Causes ... myelopathy • Transverse ... #differential #
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... • Bilateral signs ... and/or symptoms ... • Infectious causes ... management #neurology #differential
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... : CNS manifestations ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... and signs below ... Non-compressive Spinal Cord Causes ... sclerosis - Transverse ... MCTD, Sjogren syndrome
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Out Secondary Causes ... blood count with differential ... #diagnosis #hematology ... #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... and CNS • Headache ... neuropathy • Transverse ... Induced Lupus: • Symptoms
Signs and Symptoms Associated With Different Headache Etiologies
 • Nonfocal mental status changes - Meningitis, encephalitis,
Signs and Symptoms ... vasoconstriction syndrome ... #headache #signs ... #symptoms #clues ... #differential #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... • Progressive symptoms ... tract, and often causes ... chorioretinitis, CNS ... #Diagnosis #Rheumatology