12 results
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... Many others • Transverse ... pain • Extra-CNS ... Comorbid autoimmune disorders ... diagnosis #neurology #symptoms
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... - Differential ... neurological lesion: Clinical ... sclerosis - Transverse ... MCTD, Sjogren syndrome
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Myelitis - Clinical ... Weakness: - Weakness ... Bilateral signs and/or symptoms ... management #neurology #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... (CAS): - Due ... Viral Infection Clinical ... younger pts) Differential ... hemolytic #anemia #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... symptoms (headache ... (Clinical Dx). ... Behcet disease) Differential ... #rheumatology #
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... (CES) is usually ... myelopathy • Transverse ... lower extremity weakness ... #differential #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Clinical Features ... neuropathy • Transverse ... Induced Lupus: • Symptoms
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... Lymphoproliferative Disorders ... ANA #patterns #rheumatology ... #diagnosis #differential
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
anywhere in the CNS ... may mimic an LMN disorder ... form part of the differential ... LMN syndromes are ... muscle atrophy, weakness
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Myalgia and muscle weakness ... • Progressive symptoms ... chorioretinitis, CNS ... #Diagnosis #Rheumatology