14 results
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
Visual or auditory symptoms ... conjunction with symptoms ... nervous system (CNS ... optica spectrum disorder ... #inflammatory #differential
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Other brainstem syndromes ... Many others • Transverse ... pain • Extra-CNS ... Comorbid autoimmune disorders ... diagnosis #neurology #symptoms
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Focal inflammatory disorder ... that results in CNS ... Bilateral signs and/or symptoms ... Myelitis #diagnosis #management ... #neurology #differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... symptoms (headache ... Behcet disease) Differential ... #diagnosis #management ... #signs #symptoms
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... Cold Agglutinin Syndrome ... (CAS): - Due ... infection, autoimmune disorder ... younger pts) Differential
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... - Differential ... sclerosis - Transverse ... MCTD, Sjogren syndrome ... cord #spinalcord #disorders
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... (CES) is usually ... so-called ‘red flag’ symptoms ... myelopathy • Transverse ... #differential #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... ) • Endocrine disorders ... and CNS • Headache ... neuropathy • Transverse ... Induced Lupus: • Symptoms
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Periodic paralyses CNS ... Disorders: • ... • Tumor lysis syndrome ... associated with any symptoms
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
an autoimmune disorder ... thyroid, Sjogren syndrome ... life-threatening Differential ... immunosuppressants - Meds ... Gravis #diagnosis #management