21 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... HIV / AIDS - Differential ... HIV-Associated CNS ... Infections: • Most CNS ... • CNS opportunistic
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Lymphadenopathy, CNS ... or λ), Smudge Cells ... Blood #Disorders #hematology ... #Markers #Differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... peripheral neuropathy, transverse ... • 8%-27% for CNS ... Nephrogenic DI Hematologic
Approach to an Eye Exam

1. History
2. Obvious Physical Trauma
3. Initial Assessment
  A. Visual Acuity
Ocular Movements (CN ... Lids / Lashes/ Lacrimal ... Fundoscopy A. ... Ophthalmology #PhysicalExam
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... meningitis), MCC CNS ... Behcet disease) Differential ... collaboration • CNS ... signs #symptoms #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Scleromyxedema (CNS ... +GI+CVS+joints) ... +PNS+GI+Endocrine ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Guillain–Barré syndrome (GBS)
(aka: Landry–Guillain–Barré–Strohl syndrome:
	Most common cause of acute flaccid paralysis
	Rapidly progressive ascending paralysis & areflexia
	Autonomic
Guillain–Barré syndrome ... Landry–Guillain–Barré–Strohl syndrome ... Differential diagnosis ... Multiple Sclerosis: CNS ...  Transverse myelitis
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
Hypoventilation: CNS ... Hypoventilation Syndrome ... Hepatopulmonary Syndrome ... : Atelectasis, ARDS ... Hypoxia #hypoxemia #differential
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
and infects the CNS ... in the CNS ○ ... Infected cells - ... The clinical syndrome ... disorder #dementia #AIDS
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... develop leukostasis syndrome ... : CNS manifestations ... • Tumor lysis syndrome ... #Leukemia #Hematology