19 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE ... Demyelinating Syndrome ... #CNS #neurology ... #rheumatology #
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
CNS Ring-Enhancing ... - Compatible syndrome ... + toxo IgG • CNS ... 30% present w/ CNS ... @AnnKumfer #CNS
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... collaboration • CNS ... signs #symptoms #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Other brainstem syndromes ... Many others • Transverse ... pain • Extra-CNS ... Manifestations #diagnosis ... #neurology #symptoms
Lower Extremity Dermatomes and Myotomes
Reflexes: 
 • Knee - L2, L3, L4
 • Ankle - S1
Lower Extremity ... • Cauda Equina Syndrome ... Dermatomes #Myotomes #diagnosis ... #neurology #sensory ... #motor #leg #physicalexam
Upper Extremity Dermatomes and Myotomes
Motor Function
Shoulder:
 • Abduction - C5,C6 (axillary)
 • Adduction - C6, C7,
Upper Extremity ... #UpperLimb #Extremity ... Dermatomes #Myotomes #diagnosis ... #neurology #sensory ... #motor #arm #physicalexam
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... hypertension, lower extremity ... and CNS • Headache ... neuropathy • Transverse ... #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... +GI+CVS+joints) ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
(CES) is usually ... Differential Diagnosis ... myelopathy • Transverse ... #differential #diagnosis ... #causes #neurology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... nervous system (CNS ... erythematosus [SLE ... #Diagnosis #Management ... #Hematology #Rheumatology