12 results
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... sub-types based on the hematologic ... Bone lesions (CRAB ... #Significance #hematology ... #diagnosis #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... Amyloidosis and monoclonal ... ↓anion gap • CRAB ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk

#MultipleMyeloma
myeloma is not just CRAB ... actually "SLiM CRAB ... MultipleMyeloma #CRAB ... #SLIMCRAB #Oncology ... #HemeOnc #Hematology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
tissue composed of monoclonal ... percent • No CRAB ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... immunotactoid GN, Type I cryo ... ASanchez_PS #Monoclonal ... Differential #Diagnosis #hematology ... #oncology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
anti-coagulation • Hematologic ... Artery Occlusion (CRAO ... due to upstream CRAO ... seen months after CRAO ... CentralRetinalArtery #Occlusion #CRAO
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma and Monoclonal ... if this is is monoclonal ... Other causes of a monoclonal ... MGUS #diagnosis #hematology ... #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Lymphocytes) - Monoclonal ... Algorithm #Causes #Hematology ... #Oncology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
tubulopathy • Monoclonal ... change disease • Hematologic ... #AKI #Cancer #Oncology
Treatment of giant cell arteritis (GCA)

1st Line Strategy - GC 0.7 mg/kg/day, except for:
 • Aortitis
mg/kg/day (AION/CRAO ... #Indications #rheumatology