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diagnosis management hematology treatment signs symptoms causes cns disease erythematosus indications lupus monoclonal sle video workup acidosis activation algorithm alice
Alice in Wonderland Syndrome What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
• CNS: parietal ... lobe • Retina • Systemic ... • Infection (e.g ... Brain lesions (e.g ... #differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... +GI+CVS+joints) ... • Amyloidosis (CVS ... #Diagnosis #Oncology
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
papilledema • Horner syndrome ... pupil (AACG) • Systemic ... symptoms and signs (e.g ... brain lesion • CNS ... infection (e.g.
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... (e.g. oculomotor ... AQP4-lgG disease; e.g ... pain • Extra-CNS ... autoimmune disorders (Systemic
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Diagnosis Neurologic-Centered ... capillary leak syndrome ... #Diagnosis #hematology ... #oncology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
(CNS) involvement ... skull neoplasms (e.g ... MRI lesions and clinical ... #neurology #noninflammatory ... #differential #
Pisa Syndrome (pleurothotonus) on Physical Exam A tonic flexion of the trunk of the body to one
by: - drugs (e.g ... neurodegenerative disorders (eg ... Parkinson, Multiple System ... #PhysicalExam #clinical ... #neurology #posture
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 Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g ... Autoimmune diseases (e.g ... Malignancies (eg ... #oncology #diagnosis ... hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... (CNS) dysfunction ... underlying disease (eg ... • Infection (eg ... #Rheumatology
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