6 results
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... • CNS symptoms ... Get an LP and imaging ... Returning Traveler’ algorithm ... values supporting hematologic
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
membrane into the CNS ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... PBC Signs and Symptoms ... obstruction • ALP ... cholangitis #diagnosis #workup
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... pattern of spread, B symptoms ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... Treat underlying cause ... AML (~20 %) and APL
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... of about three cases ... ingestion • B symptoms ... Hodgkin Lymphoma Workup ... classification #hematology