35 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Signs and symptoms ... FLARE) (85% of pts ... predominant) (15% of pts ... Multiple Sclerosis Treatment ... management #neurology #treatment
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... for secondary causes ... glucocorticoid treatment ... organ-specific signs ... or symptoms (eg
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #signs
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
present in 15% of cases ... Antimicrobial treatment ... disorders • Symptoms ... Demyelinating disease caused ... opportunistic #InfectiousDiseases
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... dermis Clinical Signs ... /Symptoms/Exam findings ... - Erosions and crusts ... Diagnosis #Management #dermatology
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
conditions that cause ... Pathophysiology: ... pregnancy, or other causes ... , its presence is ... onset of other symptoms
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis ... #msk
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... ARDS to explain symptoms ... : 33% • Treatment ... : No • Treatment