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diagnosis differential management rheumatology dermatology algorithm causes oncology neurology hepatology systemic cancer classification skin anemia cutaneous deficiency erythematosus gastroenterology lupus
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... disorders • Celiac disease ... Damage: • Post-op surgery ... Non malignant hematologic ... effect following treatment
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... develop leukostasis syndrome ... : CNS manifestations ... • Tumor lysis syndrome ... #Hematology #Oncology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
nervous system (CNS ... and less common diseases ... diagnosis and treatment ... Vogt-Koyanagi-Harada (VKH) disease ... polychondritis • Behcet disease
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... : • Treatment: ... case by case) • Surgery ... #Syndrome #Treatment ... #pharmacology #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... Wiskott-Aldrich syndrome ... Cancer: • Leukemia ... and Autoimmune Diseases ... Differential #Diagnosis #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute leukemia ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... microglobulin Treatment ... • Richter’s Syndrome ... • Sezary syndrome ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... Waiting" →several RCTs ... chemotherapy for low-risk disease ... #oncology #hematology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Lemierre's syndrome ... Malignancy: - Hematologic ... malignancies: Lymphoma, Leukemia ... onset Still's disease ... , Kikuchi disease
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