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diagnosis rheumatology management oncology differential causes cll lymphocytic vasculitis algorithm behcet calcium classification coagulation cppd deposition dermatology dic disseminated erythematosus
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelogenous Leukemia ... : • Acute or Chronic ... disorders • Celiac disease ... Damage: • Post-op surgery ... effect following treatment
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... violaceous, nontender cutaneous ... • Tumor lysis syndrome ... #Hematology #Oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
vasculitis) • Cutaneous ... tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... Recurrent and chronic ... signs #symptoms #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Waiting" →several RCTs ... chemotherapy for low-risk disease ... uw_IMresidency #CLL #Chronic ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... cells can indicate disease ... microglobulin Treatment ... #CLL #Chronic ... workup #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... , breast CA - Hematologic ... - Lupus - Leukemia ... Treatment: - Systemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
scarring • Subacute cutaneous ... involve PNS and CNS ... vein thrombosis Hematologic ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... involvement (2%) Cutaneous ... • Severe Liver Disease ... + Bleeding Treatment ... #management #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... skin (xerosis) • Cutaneous ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... #Rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... aphthous ulcers, cutaneous ... • Cogan Syndrome ... strong sign of cutaneous ... • ANA (Suggest CTD
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