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Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential ... Vasculitis Secondary: CTD ... Vasculitis: • Behcet Disease ... • Cogan syndrome ... #differential #
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
- Malignancy: Leukemia ... Dermatoses: Sweet Syndrome ... Gangrenosum, NEH T - Treatment ... dermatoses #skin ... Rash #oncology #differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Chronic Myelogenous Leukemia ... disorders • Celiac disease ... Damage: • Post-op surgery ... effect following treatment
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... most frequent skin ... appearing during the disease ... #differential # ... diagnosis #dermatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
vasculitis) • Cutaneous ... ) Differential Diagnosis ... tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... violaceous, nontender cutaneous ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Hematology #Oncology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Cholestatic liver disease ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... Psychiatric Disease ... #generalized #dermatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... , breast CA - Hematologic ... - Lupus - Leukemia ... Treatment: - Systemic
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy
Malignancies
 - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms
Infections
 -
MIAMI Mnemonic for Differential ... Kaposi sarcoma, leukemias ... lymphomas, metastases, skin ... Bartonella), chancroid, cutaneous ... arthritis, Sjögren syndrome
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Skin manifestations ... case by case) • Surgery ... #Syndrome #Treatment ... #pharmacology #rheumatology