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diagnosis management differential oncology rheumatology algorithm causes cll lymphocytic thrombocytosis activation bariatric behcet bypass calcium cancer cirrhosis coagulation complications cppd
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelogenous Leukemia ... disorders • Celiac disease ... Damage: • Post-op surgery ... effect following treatment ... Algorithm #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Waiting" →several RCTs ... chemotherapy for low-risk disease ... uw_IMresidency #CLL #Chronic ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... cells can indicate disease ... microglobulin Treatment ... #CLL #Chronic ... workup #oncology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... Recurrent and chronic ... signs #symptoms #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... nervous system (CNS ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Complications after Bariatric Surgery Post Bariatric Intestinal Failure: • Severe protein malnutrition after bariatric surgery • More
Consider refeeding syndrome ... nutrients • TPN for treatment ... deficiencies) Dumping Syndrome ... Liver Disease in ... Gastroenterology and Hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... • Severe Liver Disease ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Myelogenous Leukemia ... • Hairy Cell Leukemia ... Myeloproliferative Disease ... #diagnosis #hematology
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