18 results
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... case by case) • Surgery ... #Syndrome #Treatment ... #management #pharmacology ... #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... develop leukostasis syndrome ... : CNS manifestations ... • Tumor lysis syndrome ... #Hematology #Oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Chronic Myelogenous Leukemia ... disorders • Celiac disease ... Damage: • Post-op surgery ... effect following treatment ... Algorithm #Causes #Hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... meningitis), MCC CNS ... tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
cells can indicate disease ... microglobulin Treatment ... • Richter’s Syndrome ... • Sezary syndrome ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... Waiting" →several RCTs ... chemotherapy for low-risk disease ... #oncology #hematology
Summary of actions of some Cholinergic Agonists

Bethanechol 
• Used in treatment of urinary retention 
• Binds
during ocular surgery ... for Alzheimer's disease ... moderate to severe disease ... in ophthalmic surgery ... Cholinergic #Agonists #Pharmacology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Puncture, EEG Treatment ... #neurology #rheumatology ... diagnosis #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... nervous system (CNS ... Treatment: • Corticosteroids ... #Rheumatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Periodic paralyses CNS ... cardiovascular surgery ... Lymphomas • Leukemias ... • Tumor lysis syndrome ... polyangiitis • Behçet's syndrome