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diagnosis management differential syndrome algorithm cerebritis cns disorders eosinophil eosinophils erythematosus hemophagocytic hes hlh hypereosinophilia leukemia lupus lymphohistiocytosis neurology oncology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... causes of eosinophilia ... are asthma, allergy ... glucocorticoid treatment ... Differential #diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
attributable to eosinophilia ... with blood eosinophilia ... Secondary Causes ... : - Allergic disorders ... #diagnosis #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
pass = Dangerous secondary ... Chronic & Rx-related Secondary ... ESRD & CAD • Eosinophilic ... Differential #Diagnosis #hematology ... #allergy
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... Puncture, EEG Treatment ... anticoagulants (for secondary ... APS), Secondary ... #neurology #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... • (Peripheral eosinophilia ... bone marrow and secondary ... #Leukemia #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
Lymphohistiocytosis (HLH) Treatment ... (depending on CNS ... transplantation Secondary ... autoimmune disease, treatment ... #management #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
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