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management diagnosis hematology anticoagulation differential algorithm antiphospholipid eular2019 guidelines lupus myopathy oncology sle systemic vte activation acute apml autoimmune breakthrough
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Demyelinating Syndrome ... (for secondary APS ... prevention (statin for CVA ... CNS #neurology #rheumatology
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
/ Breakthrough DVT ... Hypercoagulability ot Ca ... Behcet's disease - APLS ... - May-Thurner syndrome ... anticoagulation #hematology
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS Venous Thrombosis - Arterial Thrombosis INR Target Duration Recurrence Dr. Laurent ARNAUD
Antiphospholipid Syndrome ... ) APS Venous Thrombosis ... Antiphospholipid #Syndrome ... #APS #management ... #hematology #treatment
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... polymyositis overlap syndrome ... severe disease Treatment ... Summary #diagnosis #rheumatology
2019 EULAR Recommendations - Obstetrics Management in (Antiphospholipid Syndrome) APS Previous Thrombosis? Previous Pregnancy Complications? Dr. Laurent ARNAUD @Lupusreference #obstetrics
Antiphospholipid Syndrome ... ) APS Previous ... #APS #management ... EULAR2019 #guidelines #rheumatology ... #obgyn #treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... have fever - ACS ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Renal Failure Treatment ... Differentiation #Syndrome ... diagnosis #management #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... Scleromyxedema (CNS+GI+CVS ... • Amyloidosis (CVS ... beds-renal, retinal, DVT ... Paraproteinemias #Hematology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... Guillain-Barré syndrome ... systemic lupus erythematosus ... myopathies such as ... hydroxymethylglutaryl (HMG)-CoA
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
cytokines, such as ... Systemic lupus erythematosus ... systemic lupus erythematosus ... Treatment: • Corticosteroids ... #Rheumatology
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