26 results
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Diagnosis Algorithm ... Vascular System ... TeIangiectasia Vascular ... #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology ... #rheumatology #
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... abnormalities • Muscular ... #diagnosis #management ... #treatment #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell Disease ... Avascular necrosis ... #differential # ... diagnosis #causes ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... thrombocythemia), Autoimmune disease ... #Management #treatment ... #hematology #differential
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Retroperitoneum and aorta ... IgG4 #Related #Disease ... #diagnosis #management ... workup #treatment #rheumatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Diagnosis Framework ... Myeloproliferative disease ... atheroemboli) • Aorta ... pathophysiology #hematology ... diagnosis #vascular
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
and diplopia) • Vascular ... artery aneurysms Diagnosis ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Diagnosis Framework ... and bullous or vesicular ... < 30 years - Aorta ... branches • GCA: - Aorta ... #diagnosis #rheumatology
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
the wall of the aorta ... • Aortic valve disease ... Pulse deficit/differential ... Aortic #Dissection #diagnosis ... #management #vascular