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hematology classification syndrome vasculitis adultonset aortic apml arterial behcet differentiation dissection embolism hodgkins lymphoma monoclonal paraproteinemias pathophysiology pmr polymyalgia rheumatica
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... abnormalities • Muscular ... #diagnosis #management ... #treatment #rheumatology
Aortic Dissection Pearls Aortic dissection is caused by a tear in the tunica intima, the innermost layer
the wall of the aorta ... • Aortic valve disease ... Pulse deficit/differential ... Aortic #Dissection #diagnosis ... #management #vascular
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Diagnosis Framework ... Myeloproliferative disease ... atheroemboli) • Aorta ... #differential # ... diagnosis #vascular
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Diagnosis Framework ... and bullous or vesicular ... < 30 years - Aorta ... branches • GCA: - Aorta ... #diagnosis #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Cathepsin G release → vascular ... initiation • Differential ... Diagnosis: Infection ... #management #hematology ... #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
and diplopia) • Vascular ... artery aneurysms Diagnosis ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Sneddon-Wilkinson disease ... (Thrombosis in vascular ... #Monoclonal #Differential ... #Diagnosis #Oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... < 30 years • Aorta ... pulse deficits vascular ... Arteritis): • Aorta ... #Diagnosis #Rheumatology
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
Rheumatica (PMR) Diagnosis ... and Management ... no weakness or muscular ... normal and can help differentiate ... #Management #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
lymph node biopsy (diagnostic ... Immunohistochemical studies (to differentiate ... number of sites of disease ... Hodgkins #lymphoma #diagnosis ... #oncology #management
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