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diagnosis differential endocarditis negative cardiology comparison fungal infective microbiology bcnie clinical management pathology transplant abscess algorithm bacteria bloodculture bloodcultures cnie
Fungal Pneumonias - Diagnosis Comparison Table • Aspergillus • Blastomyces • Candida • Coccidioides • Cryptococcus
Diagnosis Comparison Table ... • Aspergillus ... Blastomyces • Candida ... Diagnosis #Comparison #Table ... #microbiology #infectiousdiseases
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood ... culture negative ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... #Endocarditis #InfectiousDiseases
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
bacilli - Fungi (Candida ... , Aspergillus, Histoplasma ... ) - Culture negative ... streptococci - Culture ... #Differential #InfectiousDiseases
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
Negative Blood Cultures ... therapy - Number one cause ... of culture negative ... Fungal (Histoplasma/Aspergillus ... patient a surgical candidate
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Causes of Culture ... antibiotics as a cause ... of a negative culture ... Kumfer @AnnKumfer #Culture ... Differential #Diagnosis #InfectiousDiseases
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
gut) • Fungi: Candida ... (mucosa), Aspergillus ... RSV • Fungi: Aspergillus ... differential #diagnosis #causes ... #infectiousdiseases
Common Fungal Pathology • Candida - Small yeast intermingled with pseudohyphae • Aspergillosis - Septate
Pathology • Candida ... Pathology #clinical #microscopy ... #table #atlas #
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... but important causes ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... differential #workup #infectiousdiseases
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Hypercoagulable (APLAS ... Culture (+): ... Tropheryma Whipplei • Aspergillus ... Septic Emboli Cause ... Treat underlying cause
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
preparation from culture ... exceptions are Aspergillus ... #microbiology #microscopy ... fungus #comparison #table
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