27 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... fraction < 20% Differential ... Coxsackie, CMV, EBV ... autoinflammatory diseases
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Origin (FUO) - Differential ... Brucellosis, Q fever, EBV ... , Sarcoidosis, Adult ... , Kikuchi disease ... #Origin #FUO #Differential
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
of Glomerular Diseases ... • Breaks in GBM ... #Glomerular #Diseases ... #differential # ... spectrum #diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Injury (AKI) - Differential ... Immune-complex disease ... , Anti-GBM • Tubular ... Bilateral ureteral disease ... #Diagnosis #nephrology
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
and interstitial disease ... GBM, Glomerular ... Kidney #Injury #Differential ... Causes #Sites #Nephrology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
granulomatosis: • EBV-associated ... lymphoproliferative disease ... • Metastatic disease ... Lesions #Brain #differential ... causes #radiology #neurology
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
Algorithm and Differential ... intrinsic renal disease ... prostatic) #Diagnosis #EM ... #IM #Urology #Hematuria ... #Macroscopic #Differential
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
of glomerular disease ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... Classification #Differential ... #Diagnosis #Nephrology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Epidemiology: young adults ... Immunosuppression (e.g., HIV), EBV ... infection, Autoimmune diseases ... involvement Differential ... oncology #diagnosis #differential
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... Goodpasture's Disease ... anti-ANCA ab, anti-GBM ... Renal #Syndrome #differential ... #diagnosis #nephrology