12 results
This image shows glomerular tuft with overall intact architecture. Discrete masses of specular amyloid interrupt smooth
Discrete masses ... #amyloid #desposition ... #deposits #ElectronMicroscopy ... #SEM #clinical ... #nephrology #pathology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... • Drugs Glomerular ... #Nephrology #Differential ... #Causes
This image shows a glomerular tuft with overall intact architecture. Discrete masses of specular amyloid (long
Discrete masses ... #amyloid #desposition ... #deposits #ElectronMicroscopy ... #SEM #clinical ... #nephrology #pathology
This image shows portions of glomerular tuft with collapsed GBM (across top), spicular amyloid (middle right),
shows portions of glomerular ... #GBM #amyloid #desposition ... #deposits #ElectronMicroscopy ... #SEM #clinical ... #nephrology #pathology
This image shows scanning EM of a proteinuric glomerulus with capillary loop showing widening and partial
of a proteinuric ... glomerulus with ... arkanalabs #glomerulus ... #ElectronMicroscopy ... #proteinuric #nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
hematuria and/or proteinuria ... the patient have glomerular ... hematuria (RBC casts ... Syndrome #Comparison #Algorithm ... #Nephrology #Diagnosis
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... , +/- proteinuria ... formation along glomerular ... immune deposits on EM ... Glomerulonephritis #MPGN #nephrology
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Differential Diagnosis Algorithm ... Immune-complex deposition ... nephrotic range) proteinuria ... Differential #Diagnosis #Algorithm ... #Causes
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... • Evidence of glomerular ... bleeding (proteinuria ... → Refer to Nephrology ... if cause not identified
This image shows spicular amyloid with tapering conical masses interconnected by branching fibrils!

Dr. Stephen Bonsib via
tapering conical masses ... amyloid #spicular #desposition ... #deposits #ElectronMicroscopy ... #SEM #clinical ... #nephrology #pathology