22 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... common • Imaging: CXR ... #diagnosis #management ... #hematology #oncology
Multiple Myeloma - Treatment Algorithm
a) Newly Diagnosed Myeloma: Transplant Eligible
b) Newly Diagnosed Myeloma: Transplant Ineligible

doi: 10.1038/s41408-020-00359-2

#Multiple
Multiple Myeloma - Treatment ... Algorithm a) Newly Diagnosed ... Eligible b) Newly Diagnosed ... #Algorithm #management ... #hematology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... acute leukemia Management ... only curative treatment ... #Management #treatment ... #hematology #oncology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... #Disease #diagnosis ... #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... #AdultOnset #Stills ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... manifestations, hypoxia, CXR ... smear: Blasts APML ... #Leukemia #Hematology ... #Oncology #Diagnosis
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... Summary Diagnostic ... transformation into AML ... #Management #Summary ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... organ damage • Treatment ... acid, Elevated Cr ... Syndrome #TLS #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... transformation) Treatment ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology # ... management