16 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... manifestations, hypoxia, CXR ... smear: Blasts APML ... #Leukemia #Hematology ... #Oncology #Diagnosis
Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm

By Matthew Ho, MD PhD @MatthewHoMD

#Diffuse
Diffuse large B cell ... lymphoma (DLBCL) - Management ... and Treatment Algorithm ... #Treatment #Algorithm ... #oncology #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... common • Imaging: CXR ... #diagnosis #management ... #hematology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Summary myelo ... Allogeneic stem cell ... only curative treatment ... #treatment #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... microglobulin Treatment ... Transform to DLBCL, PML ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
) - Summary Overview ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... Summary Diagnostic ... transformation into AML ... #Summary #treatment ... #hematology
Perilunate Dislocation
On lateral wrist XR, the capitate ("apple") should sit in the lunate ("tea cup") which
lateral wrist XR ... Here's quick summary ... recommendations; ill ... #Radiology #XRay ... #Diagnosis #Management
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... syndrome): - Hematologic ... interventional radiology ... ± tocilizumab; call ... (~20 %) and APL
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
lymphoma, B-cell ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology