9 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... organ damage • Treatment ... acid, Elevated Cr ... TLS #diagnosis #management ... #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #pharmacology # ... treatment #medications ... #decisionaid #cardiology ... #hematology #warfarin
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Symptoms (DRESS) Syndrome ... Treatment Stop ... LFTs daily • Cr ... #Treatment #Management ... #dermatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Behcets #disease #Syndrome ... #Treatment #management ... #pharmacology # ... rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... common • Imaging: CXR ... APML #diagnosis #management ... #hematology #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... - Compartment syndrome ... - Fever - Tachycardia ... ) • AKI: BUN/Cr ... Differential #Diagnosis #Management
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... , hypotension, tachycardia ... edema, compartment syndrome ... #diagnosis #management ... #rheumatology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
& Dry) is the treatment ... acute coronary syndrome ... differential #algorithm #management ... #cardiology #treatment ... icu #clinical #pharmacology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... Diagnosis #Management