48 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... expansion (e.g. carpal ... metabolic abn #GrowthHormone ... endocrinology #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
overgrowth: • Carpal ... fraction • HTN #GrowthHormone ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Concussion - Acute Pathophysiology

#Concussion #Pathophysiology #neurology #signs #symptoms
Concussion - Acute Pathophysiology ... #Concussion #Pathophysiology ... #neurology #signs ... #symptoms
Central Retinal Vein Occlusion (CRVO): Pathogenesis and clinical findings

#CentralRetinalVein #Occlusion #CRVO #pathophysiology #ophthalmology #diagnosis #signs #symptoms
Occlusion #CRVO #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
exertion • Neurologic ... dysrhythmias • Ophthalmologic ... Sarcoidosis #Diagnosis #Symptoms ... #Signs #Pulmonary
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Signs and symptoms ... Multiple Sclerosis Treatment ... objective evidence of neurologic ... diagnosis #management #neurology ... #treatment #MS
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Chondrodysplasia Neurologic ... in the Spinal canal ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis
Thyrotoxic Periodic Paralysis - Illness Script
 • Epidemiology: Asian men age 20-30 with hyperthyroidism of any
and menses • Pathophysiology ... thyroid hormone • Symptoms ... /signs: Episodes ... hours-days duration +/- symptoms ... or high T3 • Treatment